Animated film visualises links between oral and general health – watch the trailer now
Oral health animation
The trailer for a joint Sunstar and Quintessence film production on the links between oral and general health, to be released in November, is now available for viewing via the link at the end of this news item.
The 3D scientific video animation Oral Health and General Health: The Links between Periodontitis, Atherosclerosis, and Diabetes explores the scientific question of whether periodontitis and other inflammatory processes of the oral cavity contribute to the development of general diseases or negatively influence their course.
Specialist input was provided by an international team of experts including the authors Prof Hendrik Terheyden (Germany), Dr Bernd Stadlinger (Switzerland), Prof Søren Jepsen (Germany), and Prof Mariano Sanz (Spain), as well as an advisory board whose members were Prof Iain Chapple (UK), Prof Robert Genco (USA), Prof Evanthia Lalla (USA), and Prof Shinya Murakami (Japan).
This scientific project is supported by the Sunstar Foundation and Sunstar, and produced by the Quintessence International Publishing Group. Project manager Dr Alexander Ammann and coordinator Änne Klebba of Quintessence Publishing have played a key role in its successful completion, as well as 3D specialists Dr Marko Reschke, Thomas Kramer, and Matthias Gauer of the interActive Systems Berlin animation company (a subsidiary of Quintessence). Additionally, Fumihiro Awashima and Dr Marzia Massignani of oral-healthcare product provider Sunstar, which is an EFP partner, have contributed.
This is the fourth film in the Cell-to-Cell Communication series, which Quintessence Publishing launched in 2011 with the aim of making the complex network of communication and information exchange between human body cells visible, using 3D animations to display and explain microscopic processes.
Oral Health and General Health addresses its subject by visualising the highly complex intercellular interactions and signalling pathways in the development and progression of general diseases caused by periodontitis. The film gives particular attention to atherosclerosis and type 2 diabetes.
The four main areas covered by the film are:
The dissemination of bacteria in periodontitis;
Impact of periodontitis on the cardiovascular system: atherosclerosis;
The effect of periodontitis on glucose metabolism: type 2 diabetes; and
“Periodontal pathogens are invasive and can spread throughout the body via the bloodstream,” says the preface to the booklet which accompanies the film. “They can penetrate the vascular walls and proliferate in the endothelium. The immune response to these pathogens can lead to atherogenesis in the vascular walls and induce potentially lethal damage.”
The introduction adds that the other area of concern is the pro-inflammatory cytokines that are released in chronic periodontitis, which “can react with the cells’ insulin receptors and thereby inhibit the transport of glucose into the cells, driving up blood sugar levels and causing excessive insulin secretion all the way to peripheral insulin resistance – fully-fledged type 2 diabetes mellitus.”
The film was well received at its premiere in the main auditorium at EuroPerio8 in London on June 4, in a session moderated by Prof Sanz and Prof Stadlinger.
There are two versions of the film: the “expert” version (which was shown at EuroPerio8) and a version aiming at the general public.
A hardcover DVD premium edition containing both versions on separate DVDs – together with the storyboard, a questionnaire for students, details about the team of experts and the technical equipment used, and a scientific review article – is due to be released in November.
The scientific review article will also be published this autumn as a guest editorial in the EFP’s Journal of Clinical Periodontology.
Sunstar, a globally recognized leader in the oral care industry, has been providing research-based products and services in 90 countries for over 80 years. Sunstar was one of the first companies to advocate the new thinking on the integral relationship between oral and systemic health. Sunstar is committed to pursuing research and development through joint-research projects with leading world research institutions as well as dental and medical experts around the world. Sunstar manufactures an extensive line of preventive and therapeutic products under the brands Gum, Butler, and Guidor.
The Quintessence International Publishing Group, founded in 1949 in Berlin, Germany, is an internationally leading publishing house committed to quality and providing the latest scientific and clinical information to meet the varying needs of the dental community. Quintessence Publishing is represented with its own publishing houses in 16 countries and collaborates with licensing partners in another seven countries. Meeting the needs of beginning dental students, experienced practitioners as well as researchers, the company publishes 66 professional journals in 21 languages. The journal list includes nine peer-reviewed journals with an impact factor.
Besides a list of more than 1,500 specialist book titles, Quintessence Publishing offers over 450 videos – produced in its own film studio and made available through its online video library, as well as a large collection of CD-ROMs, DVDs and multimedia programs. It collaborates with more than 3,500 authors worldwide, and organises national and international congresses, symposia and workshops.