The modified minimally invasive surgical technique (M-MIST) was developed to treat intrabony defects as a way to reduce flap dimensions, healing time, and patient discomfort and to improve wound stability.
A 10-year follow-up of a randomised controlled trial, now summarised as JCP Digest 102, sought to compare the long-term stability of outcomes using the M-MIST technique alone and in combination with enamel matrix derivative (EMD) and bone-mineral-derived xenograft (BMDX).
Researchers Pierpaolo Cortellini, Simone Cortellini, Daniele Bonaccini, and Maurizio S. Tonetti found that teeth presenting intrabony defects associated with deep pockets can be successfully treated with an M-MIST approach, whether or not regenerative material is also used.
They also concluded that avoiding regenerative material provides the same short- and long-term benefits as a regenerative approach with biomaterials but at a lower cost.
The research was summarised for JCP Digest by postgraduate students at the EFP-accredited programme in periodontology at the International University of Catalonia in Barcelona, Spain.